Phosphatidylglycerol Supplementation Alters Mitochondrial Morphology and Cardiolipin Composition
The pathogenic variant of the TAZ gene is directly Bowl Mount associated with Barth syndrome.Because tafazzin in the mitochondria is responsible for cardiolipin (CL) remodeling, all molecules related to the metabolism of CL can affect or be affected by TAZ mutation.In this study, we intend to recover the distortion of the mitochondrial lipid compos